Kathleen Liu, MD, PhD | UCSF Adult Medical Surgical ICU

Professor In Residence

M_MED-CORE-NEPH-GEN

EDUCATION

College: Harvard University, AB
Medical/Graduate School: University of California, San Francisco, MD, PhD

RESEARCH

My current research areas of interest focus on the predictive and pathogenetic role of biomarkers for both acute and chronic disease states. My long term goal is to identify and validate novel biomarkers of organ injury (specifically, the kidney and lung) that may have predictive value for disease outcomes as well as shed important insight into disease pathogenesis. In addition, I have a major interest in clinical trials in the Intensive Care Unit, with a particular focus on acute lung injury and acute kidney injury.

Publications

A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury: The Liberation From Acute Dialysis (LIBERATE-D) Randomized Clinical Trial.

JAMA

Liu KD, Siew ED, Tuot DS, Vijayan A, Matzumura Umemoto G, Birkelo BC, Lee BJ, Kwong YD, McCoy IE, Delucchi K, Zhuo H, Hsu CY

Time-limited trials for acute dialysis decision-making for critically ill older patients: rationale, communication strategies, and future research.

Current opinion in nephrology and hypertension

Saeed F, Duberstein PR, White DB, Liu KD, Epstein RM, Fiscella KA

Effects of IV Acetaminophen on Core Body Temperature and Hemodynamic Responses in Febrile Critically Ill Adults: A Randomized Controlled Trial.

Critical care medicine

Schell-Chaple HM, Liu KD, Matthay MA, Sessler DI, Puntillo KA

Urine Kidney Injury Biomarkers and Risks of Cardiovascular Disease Events and All-Cause Death: The CRIC Study.

Clinical journal of the American Society of Nephrology : CJASN

Park M, Hsu CY, Go AS, Feldman HI, Xie D, Zhang X, Mifflin T, Waikar SS, Sabbisetti VS, Bonventre JV, Coresh J, Nelson RG, Kimmel PL, Kusek JW, Rahman M, Schelling JR, Vasan RS, Liu KD

Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup.

Nature reviews. Nephrology

Chawla LS, Bellomo R, Bihorac A, Goldstein SL, Siew ED, Bagshaw SM, Bittleman D, Cruz D, Endre Z, Fitzgerald RL, Forni L, Kane-Gill SL, Hoste E, Koyner J, Liu KD, Macedo E, Mehta R, Murray P, Nadim M, Ostermann M, Palevsky PM, Pannu N, Rosner M, Wald R, Zarbock A, Ronco C, Kellum JA

Higher mini-BAL total protein concentration in early ARDS predicts faster resolution of lung injury measured by more ventilator-free days.

American journal of physiology. Lung cellular and molecular physiology

Hendrickson CM, Abbott J, Zhuo H, Liu KD, Calfee CS, Matthay MA

Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Waikar SS, Sabbisetti V, Ärnlöv J, Carlsson AC, Coresh J, Feldman HI, Foster MC, Fufaa GD, Helmersson-Karlqvist J, Hsu CY, Kimmel PL, Larsson A, Liu Y, Lind L, Liu KD, Mifflin TE, Nelson RG, Risérus U, Vasan RS, Xie D, Zhang X, Bonventre JV

ATS Core Curriculum 2016: Part II. Adult Critical Care Medicine.

Annals of the American Thoracic Society

McSparron JI, Hayes MM, Poston JT, Thomson CC, Fessler HE, Stapleton RD, Carlos WG, Hinkle L, Liu K, Shieh S, Ali A, Rogers A, Shah NG, Slack D, Patel B, Wolfe K, Schweickert WD, Bakhru RN, Shin S, Sell RE, Luks AM

Extracorporeal treatment for theophylline poisoning: systematic review and recommendations from the EXTRIP workgroup.

Clinical toxicology (Philadelphia, Pa.)

Ghannoum M, Wiegand TJ, Liu KD, Calello DP, Godin M, Lavergne V, Gosselin S, Nolin TD, Hoffman RS

Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus.

Diabetologia

Fufaa GD, Weil EJ, Nelson RG, Hanson RL, Bonventre JV, Sabbisetti V, Waikar SS, Mifflin TE, Zhang X, Xie D, Hsu CY, Feldman HI, Coresh J, Vasan RS, Kimmel PL, Liu KD

Rosuvastatin for sepsis-associated ARDS.

The New England journal of medicine

Liu KD, Dong N, Truwit JD

Acute kidney injury: an increasing global concern.

Lancet (London, England)

Lameire NH, Bagga A, Cruz D, De Maeseneer J, Endre Z, Kellum JA, Liu KD, Mehta RL, Pannu N, Van Biesen W, Vanholder R

The EXTRIP (EXtracorporeal TReatments In Poisoning) workgroup: guideline methodology.

Clinical toxicology (Philadelphia, Pa.)

Lavergne V, Nolin TD, Hoffman RS, Roberts D, Gosselin S, Goldfarb DS, Kielstein JT, Mactier R, Maclaren R, Mowry JB, Bunchman TE, Juurlink D, Megarbane B, Anseeuw K, Winchester JF, Dargan PI, Liu KD, Hoegberg LC, Li Y, Calello DP, Burdmann EA, Yates C, Laliberté M, Decker BS, Mello-Da-Silva CA, Lavonas E, Ghannoum M

Acute kidney injury: is acute kidney injury a risk factor for long-term mortality?

Nature reviews. Nephrology

Liu KD